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Healing

Pentosan Polysulfate (PPS)

A semi-synthetic glycosaminoglycan with anti-inflammatory and cartilage-protective properties. FDA-approved for interstitial cystitis, also used for joint and cartilage repair.

100 mg vialHalf-life: 4.8 hours3x weeklyStandard · ≤10 mg/mL
Order: Coming soon

Overview

Clinical Benefits
  • Cartilage protection and repair
  • Joint health support
  • Anti-inflammatory
  • Bladder health
Administration

Subcutaneous injection or oral capsule

Drug class: glycosaminoglycan

Clinical Dosing

Typical dosage
100mg
Starting dose
100mg
Cadence
3x weekly
Full titration schedule
PhaseDose
Weeks 1-12100mg three times weekly (subcutaneous or oral)

Safety Profile

Side effects
  • • Headache
  • • GI discomfort
  • • Hair thinning (rare, reversible)
Contraindications
  • • Bleeding disorders
  • • Anticoagulant therapy

Frequently asked questions

Pentosan Polysulfate (PPS) is most commonly researched for: Cartilage protection and repair, Joint health support, Anti-inflammatory, Bladder health.

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Information on this page is for educational purposes only and is not medical advice. Peptides should only be used under the supervision of a qualified healthcare provider.

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