Overview
Clinical Benefits
- Sleep quality (lowers core body temp)
- Collagen synthesis (1/3 of collagen is glycine)
- Glutathione precursor
- Anti-inflammatory
- GABA-like calming effect
Administration
Oral powder (most common, lowers core temp for sleep) or added to IV drips
Drug class: amino acid
Clinical Dosing
Typical dosage
1-3g oral pre-bed, or 500mg-1g IV
Starting dose
1g oral / 500mg IV
Cadence
Once daily (pre-bed)
Full titration schedule
| Phase | Dose |
|---|---|
| Weeks 1-2 | 1g oral pre-bed (or 500mg added to IV drip) |
| Weeks 3+ | 3g oral pre-bed for sleep / 1g IV per drip |
Safety Profile
Side effects
- • Mild GI upset at high oral doses (>10g)
- • Drowsiness
- • Very well tolerated
Contraindications
- • Severe renal impairment
- • Hyperammonemia
Frequently asked questions
Glycine is most commonly researched for: Sleep quality (lowers core body temp), Collagen synthesis (1/3 of collagen is glycine), Glutathione precursor, Anti-inflammatory.
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Information on this page is for educational purposes only and is not medical advice. Peptides should only be used under the supervision of a qualified healthcare provider.